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Take control of your health with TruHealth!
A cutting-edge diagnostic test based on advanced DNA methylation analysis evaluates over 110 epigenetic biomarkers and provides an in-depth assessment of systemic health at the cellular level.
Take control of your health with TruHealth!
A cutting-edge diagnostic test based on advanced DNA methylation analysis evaluates over 110 epigenetic biomarkers and provides an in-depth assessment of systemic health at the cellular level.
Take control of your health with TruHealth!
A cutting-edge diagnostic test based on advanced DNA methylation analysis evaluates over 110 epigenetic biomarkers and provides an in-depth assessment of systemic health at the cellular level.
TruHealth algorithms
TruHealth analyzes +110 key epigenetic biomarkers assessing cellular health in key systems associated with longevity! TruHealth provides accurate and evidence-based recommendations to improve health at the cellular level, enabling personalized interventions to prevent chronic disease and enhance overall well-being.
Nutrient levels
Optimize vitamin and mineral levels for better health.
Metabolic health
Understanding metabolism for improved energy and weight control.
Intestinal health
Assessment of digestion and nutrient absorption for general wellbeing.
Inflammation and immunity
Identification of underlying inflammation affecting immunity and overall health.
Brain health
Identifying biomarkers for memory, concentration and long-term brain health.
Antioxidant defence
Measuring the body's ability to fight free radical damage.
Toxic loads
Detecting exposure to heavy metals and chemicals from the environment.
Healthy fats
Optimizing the balance of omega fatty acids for heart health.
Cellular energy
Assessing the efficiency of cellular energy production for vitality.
TruHealth epigenetic biomarkers
TruHealth reveals important biomarkers related to disease prevention, metabolic function, nutrition, immune health, mitochondrial activity, and toxic load.
Vitamins | Vitamin A (retinol), B2 (riboflavin), B3 (nicotinamide), B5 (pantothenic acid), B6 (pyridoxine, pyridoxine-5-phosphate), B7 (biotin), B8 (inositol, myo-inositol), D (cholecalciferol), E (alpha-tocopherol), C (ascorbic acid 2-sulfate, ascorbic acid 3-sulfate). |
Amino acids | Methionine, cysteine, S-methylmethionine, taurine, glutamine, arginine, tyrosine, L-aspartic acid, asparagine, threonine, glycine, carnosine, cystathionine, histidine, citrulline, valine, N-carbamoylvaline, N-acetylvaline. |
Methylation | Riboflavin, pyridoxine, pyridoxine-5-phosphate, methionine, choline, betaine. |
Antioxidants | Retinol, N-acetylcysteine, carotenoids, S-adenosylglutathione, acetyl-L-carnitine, ergothioneine, uric acid. |
Minerals | Iron, magnesium, potassium, calcium, copper. |
Healthy fats | DHA, DPA, EPA, omega-3, omega-6, pentadecanate. |
Lipid peroxidation | Phospholipase A2, glutathione peroxidase, octadecadienedioate (C18:2-DC). |
Metabolism | HbA1c, glucose, lipolysis markers. |
Immune markers | The number of leukocytes, neutrophils, lymphocytes. |
Bones | Phosphorus. |
Neurocognitive health | Brain aging marker, memory health protein, brain inflammation marker, dopamine metabolites, cellular repair marker, anti-inflammatory brain protein. |
Microbiome | Gut and immune barrier, indicator of bacterial toxins, marker of phenylalanine dysbiosis, marker of gut and brain health. |
Inflammation | IL-6, a marker of oxidative stress, and serum amyloid A-1 protein. |
Stress | Cortisol, DHEA, a marker of adrenal activity, a marker of chronic stress. |
Toxins | Acrolein, polycyclic aromatic hydrocarbons, pesticides, lead exposure, PFAS (per- and polyfluorinated substances). |
Mitochondrial function | Energy balance marker, ATP synthase (enzyme), energy transport protein, energy regulation enzyme. |
Antioxidant defence | Myeloperoxidase (MPO), marker of ROS production, indicator of oxidative stress, marker of oxidative damage, heat shock proteins (defense against cellular stress). |
NAD+ metabolism | Byproduct marker, nicotinamide, nicotinamide riboside, 1-MNA. |
Ketones | Beta-hydroxybutyrate, acetoacetate. |
Additives | Alpha-ketoglutarate, spermidine, palmitoylethanolamide, creatine. |
Comprehensive testing
TruHealth's comprehensive testing, based on the analysis of epigenetic biomarkers, helps to identify the root causes of various chronic diseases and conditions with high accuracy:
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- Mental disorders: depression, attention deficit hyperactivity disorder (ADHD);
- Metabolic and endocrine disorders: obesity, type 2 diabetes, hypothyroidism, polycystic ovarian syndrome (PCOS), weight problems;
- Cardiovascular and immune diseases: hypertension, immunodeficiency, autoimmune diseases;
- Digestive problems: malnutrition (especially in the elderly), digestive disorders and malabsorption;
- Oncology and chronic conditions: cancer, chronic fatigue;
- Reproductive health: infertility;
- Athletic aspects: recovery, healing, and sports performance evaluation.
TruHealth report
Includes clinically relevant findings and practical, science-based recommendations, on nutrition, lifestyle, supplements and more to optimize key indicators of health at the cellular level.
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Personalized recommendationsPersonalized nutrient recommendations (vitamins, minerals, amino acids, fatty acids, digestive support) based on detailed analysis of key biomarkers. - Functional health metricsFunctional health metrics with built-in scoring system for therapies targeting methylation, toxic load, mitochondrial health, fatty acid balance, and oxidative stress.
- Clear explanationsClear pages with explanations of the role of nutrients, the causes and effects of nutrient deficiencies, and food sources.
- Interactive diagramsInteractive diagrams of biochemical pathways showing the influence of biomarkers on key biochemical processes.
This section includes a comprehensive review of common markers of health and nutrition, each based on one or more epigenetic biomarkers that reflect cellular health and function.
The percentile ranking of biomarkers indicates how your health status compares to the wider population, allowing you to understand where interventions may be needed or where they are already performing well.
For example, a score of 0 indicates the worst possible outcome (potential area of risk or concern), a score of 100 indicates the best possible outcome, emphasizing areas of optimal health.
The percentile ranking of biomarkers indicates how your health status compares to the wider population, allowing you to understand where interventions may be needed or where they are already performing well.
For example, a score of 0 indicates the worst possible outcome (potential area of risk or concern), a score of 100 indicates the best possible outcome, emphasizing areas of optimal health.
This section includes recommendations that target the areas with the greatest potential for improvement, providing practical and individualized steps to achieve an ideal health profile.
This section shows the activity of your genes based on epigenome analysis.
Your biomarkers are compared to the results of other people (reference group) and expressed as a percentage: from 0% (lowest level) to 100% (highest). For every biomarker, there is an ideal level that is best for health: low, medium, or high:
Your biomarkers are compared to the results of other people (reference group) and expressed as a percentage: from 0% (lowest level) to 100% (highest). For every biomarker, there is an ideal level that is best for health: low, medium, or high:
- If the ideal level is low, the best result is 0%.
- If the ideal level is average, the best result is 50%.
- If the ideal level is high, the best result is 100%.
CHOOSE YOUR PATH TO HEALTH AND LONGEVITY
With advanced epigenetic tests based on DNA methylation!
Developed together with leading US universities: Harvard, Yale, Duke, Cornell.
TruAge
Assessment of aging and longevity based on +75 epigenetic biomarkers
9 900 lei
Timeframe: 3 weeks
Timeframe: 3 weeks
TruHealth
Health assessment based on
+110 epigenetic biomarkers
+110 epigenetic biomarkers
9 900 lei
Timeframe: 3 weeks
Timeframe: 3 weeks
TruAge + TruHealth
Comprehensive health assessment
and aging in one test
and aging in one test
12 900 lei
Timeframe: 3 weeks
Timeframe: 3 weeks
Frequently asked questions
Epigenetics studies the interaction of your genes with external factors. That is, how sleep, nutrition, stress, physical activity, environment, and other factors regulate the activity (expression) of genes through chemical modifications to DNA, such as methylation, without changing its sequence
- Epigenetics studies the activity of genes under the influence of internal and external environmental factors.
TruAge is the most advanced, accurate and scientifically validated epigenetic test that determines biological age, rate of aging and age of individual organs. Given that aging is the #1 risk factor for virtually all chronic diseases and death, slowing aging can significantly reduce these risks.
In simple words: The test shows you how your body is aging and gives you recommendations on how to slow down aging.
Scientifically speaking: TruAge uses high-throughput DNA methylation sequencing to assess epigenetic age and systemic aging using algorithms validated on the Dunedin and Framingham cohorts.
In simple words: The test shows you how your body is aging and gives you recommendations on how to slow down aging.
Scientifically speaking: TruAge uses high-throughput DNA methylation sequencing to assess epigenetic age and systemic aging using algorithms validated on the Dunedin and Framingham cohorts.
TruAge focuses on aging, while TruHealth focuses on health.
In simple terms: TruAge "watches" how you age and TruHealth watches how you live now.
Scientifically speaking: TruAge assesses the epigenetic clock and systemic aging, while TruHealth analyzes methylation associated with ongoing metabolic and immune processes.
In simple terms: TruAge "watches" how you age and TruHealth watches how you live now.
Scientifically speaking: TruAge assesses the epigenetic clock and systemic aging, while TruHealth analyzes methylation associated with ongoing metabolic and immune processes.
Epigenetic biomarkers are specific biological markers obtained by analyzing DNA methylation patterns in your genome.
The uniqueness of epigenetic biomarkers lies in their dynamism, as they are formed by the interaction of genes and environmental factors (nutrition, lifestyle, exposure to toxins and stress levels)
Epigenetic biomarkers provide unique insights into ongoing biological functions by predicting levels of nutrients, metabolites, and other important biochemical compounds.
Their main advantage is their ability to detect hidden imbalances and potential risks earlier than traditional laboratory biomarkers. This makes them a valuable tool in personalized medicine, nutrigenetics and preventive strategies for health maintenance.
Epigenetic biomarkers are not equal to clinical laboratory tests, but complement rather than replace them. On average, epigenetic biomarkers are superior to traditional laboratory biomarkers in both prediction and diagnosis:
Epigenetic biomarkers can predict the development of (help diagnose) 12 major chronic diseases: cardiovascular, type 2 diabetes, chronic kidney disease, cognitive impairment, and all-cause mortality.
Epigenetic biomarkers demonstrate 90% overall accuracy in detecting deviations from clinical norms; high specificity (94%) and sensitivity (76%) in clinical laboratory tests.
EBs provide a more stable and comprehensive view of your health over time, reflecting long-term impacts and trends rather than short-term fluctuations (as with lab markers).
The uniqueness of epigenetic biomarkers lies in their dynamism, as they are formed by the interaction of genes and environmental factors (nutrition, lifestyle, exposure to toxins and stress levels)
Epigenetic biomarkers provide unique insights into ongoing biological functions by predicting levels of nutrients, metabolites, and other important biochemical compounds.
Their main advantage is their ability to detect hidden imbalances and potential risks earlier than traditional laboratory biomarkers. This makes them a valuable tool in personalized medicine, nutrigenetics and preventive strategies for health maintenance.
Epigenetic biomarkers are not equal to clinical laboratory tests, but complement rather than replace them. On average, epigenetic biomarkers are superior to traditional laboratory biomarkers in both prediction and diagnosis:
- 62% of epigenetic biomarkers are more strongly associated with disease progression.
- 64% of epigenetic biomarkers are diagnostically more significant.
- Epigenetic biomarkers demonstrate 90% accuracy in detecting abnormalities from clinical norms.
Epigenetic biomarkers can predict the development of (help diagnose) 12 major chronic diseases: cardiovascular, type 2 diabetes, chronic kidney disease, cognitive impairment, and all-cause mortality.
Epigenetic biomarkers demonstrate 90% overall accuracy in detecting deviations from clinical norms; high specificity (94%) and sensitivity (76%) in clinical laboratory tests.
EBs provide a more stable and comprehensive view of your health over time, reflecting long-term impacts and trends rather than short-term fluctuations (as with lab markers).
TruHealth is a test designed to assess your current state of health at the cellular level using 110+ epigenetic biomarkers related to nutrition, metabolism, hormone balance, antioxidant defense, immunity, cognitive health, etc.
In simple words: The test checks if everything is okay with your health and what needs improvement.
In scientific terms: TruHealth is designed to help physicians identify underlying causes of dysfunction and correct clinical imbalances that prevent optimal health. This advanced diagnostic tool provides a systematic approach to help physicians help their patients overcome chronic diseases and lead healthier lives.
In simple words: The test checks if everything is okay with your health and what needs improvement.
In scientific terms: TruHealth is designed to help physicians identify underlying causes of dysfunction and correct clinical imbalances that prevent optimal health. This advanced diagnostic tool provides a systematic approach to help physicians help their patients overcome chronic diseases and lead healthier lives.
The patient takes a capillary blood sample (finger prick) at any Alfa Diagnostica Testing Center. No preparation for the test is required. The turnaround time for the test varies from 2 to 3 weeks.
In simple words: It's a simple finger prick, like a sugar test, and the result in a couple weeks.
Scientifically speaking: The analysis is performed using Illumina microarrays for DNA methylation sequencing from capillary blood, with data processing in a CLIA-certified laboratory.
In simple words: It's a simple finger prick, like a sugar test, and the result in a couple weeks.
Scientifically speaking: The analysis is performed using Illumina microarrays for DNA methylation sequencing from capillary blood, with data processing in a CLIA-certified laboratory.
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